big business

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These concerns have made the care of cats into big business.
这种关心使得对猫的照顾成为一项大生意。
Moreover, while all this is happening, immigrants are allegedly streaming into the US, partly at the behest of big business, to keep the labour market weak.
此外，尽管这一切都在进行，但移民们声称，他们涌入美国部分是因为大财团一直希望劳动力市场保持虚弱。
Or might there be another explanation for why we find such a marked shortage of women, not just in the highest levels of science but in big business, the professions, and politics, too?
关于为什么我们发现不仅在科学界的高层女性特别少，大企业、专业领域还有政界也不例外，这可能还有其他的解释吗？

My mother was a teacher. My father had planned to become a big business man, but he became a social worker instead.
Now Microsoft is sort of a funny place, we've got these big businesses but in the software business big businesses need to be constantly recreated.
现今的微软是非常有意思的地方，我们运行着庞大的生意，但是在软件交易上,大宗交易更像是消遣。
斯坦福公开课 - 微软CEO-Steve.Ballmer谈科技的未来课程节选
you know. So, it's a big business.
你知道。所以，这是件大事。
帕丽斯·希尔顿 - SpeakingMax英语口语达人

Consumers seemed to think that the weather would translate into big business for Big Box retailers.
FORBES: Hurricane Irene Beats Up The Northeast And The Fragile U.S. Economy

(BUSINESS) powerful and influential businesses and financial organizations (= ones with a lot of influence) when considered as a group
(POPULAR) something that makes a lot of money

Big business is business which involves very large companies and very large sums of money.
Something that is big business is something which people spend a lot of money on, and which has become an important commercial activity.