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The pathological characteristics observed as depressed, dipsa and appetite were descended, diarrhea, weak legs, turbid eyes, opisthotomus, swelling head, and arthrophyma. 临床病理特征均表现为精神萎靡，饮食欲下降，腹泻，腿软无力，眼睛浑浊，呼吸困难，脚蹼反张等、头部肿胀，关节肿大。