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The studies by Caprai et al6 and Cosnes et al10 included in this issue of Clinical Gastroenterology and Hepatology support the association between CD and other autoimmune disorders. 乳糜泻患者损伤肠道的治疗配合低麦胶饮食可能使肠道通透性正常，减少暴露引起自身免疫的因素。